Our Science

  • OPCML tumor suppressor therapy effectively replaces a crucial protein that blocks cancer in over half of all human solid cancers


  • OPCML therapy acts at the cell surface, without the need to restore the tumor suppressor inside every cancer cell


  • Restoration of OPCML reverses the cancer state as well as activating anti-tumor immunity


  • OPCML tumor suppressor therapy synergizes with chemotherapy, RTK inhibitors and immunotherapy


  • Predictive biomarkers can select patients likely to benefit


  • In addition to tumor suppressor protein replacement therapy, gene replacement therapy can be considered


  • Initial lines of sight include brain, colorectal and ovarian tumors