Our Science

  • OPCML tumor suppressor therapy effectively replaces a crucial protein that blocks cancer in almost half of all human cancers

 

  • OPCML therapy acts at the cell surface, without the need to restore the tumor suppressor inside every cancer cell

 

  • Restoration of OPCML reverses the cancer state as well as activating anti-tumor immunity

 

  • It therefore functions in cancer like insulin for diabetes

 

  • OPCML tumor suppressor therapy synergizes with chemotherapy, RTK inhibitors and immunotherapy

 

  • Predictive biomarkers can select patients likely to benefit

 

  • In addition to tumor suppressor protein replacement therapy, gene replacement therapy can be considered

 

  • Initial lines of sight include brain, colorectal and ovarian tumors